Evaluation of desensitizing efficacy of nanohydroxyapatite on the treatment of dentine hypersensitivity following ultrasonic scaling: a randomized controlled trial

Objective: This randomized controlled trial aimed to compare nanohydroxyapatite with fluoride on managingpost ultrasonic scaling Dentine hypersensitivity (DH). Material and Methods: Thirty patients (aged 20-50years) post ultrasonic-scaling DH were included in this study. The sample was randomly divided into threeequal groups of 60 teeth each: the first group received material, second receivedfluoride material third sterile water as a placebo (controls). materials appliedonce for each patient. All instructed rate level pain before treatment, after 1 hour, 24hours, 2 weeks month numerical rating scale (NRS). Kruskal-Wallis test, Mann-Whitney tests,linear regression analysis used statistical analysis. Significance set at 0.05. Results: Bothnanohydroxyapatite successful reducing associated when compared theplacebo subsequent follow-ups (p < 0.05). However, one-hour one-day application, nanohydroxyapatitecould reduce more effectively than Conclusion: Nanohydroxyapatitematerial found be significantly effective that followed one-hourand application water. Both nanohydroxyapatitehad similar effect two-weeks one-month application. KEYWORDSDentine hypersensitivity; Desensitizing agent; Fluoride; Nanohydroxyapatite; Ultrasonic scaling.